Structures of H5N1 influenza polymerase with ANP32B reveal mechanisms of genome replication and host adaptation
Abstract Avian influenza A viruses (IAVs) pose a public health threat, as they are capable of triggering pandemics by crossing species barriers. Replication of avian IAVs in mammalian cells is hindered by species-specific variation in acidic nuclear phosphoprotein 32 (ANP32) proteins, which are esse...
| Autori principali: | , , , , , , , , |
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| Natura: | Articolo |
| Lingua: | English |
| Pubblicazione: |
Nature Portfolio
2024-05-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-024-48470-3 |