In silico assessment of histotripsy-induced changes in catheter-directed thrombolytic delivery

Introduction: For venous thrombosis patients, catheter-directed thrombolytic therapy is the standard-of-care to recanalize the occluded vessel. Limitations with thrombolytic drugs make the development of adjuvant treatments an active area of research. One potential adjuvant is histotripsy, a focused...

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Bibliographic Details
Main Authors: Kenneth B. Bader, Katia Flores Basterrechea, Samuel A. Hendley
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1225804/full