Overactive autophagy is a pathological mechanism underlying premature suture ossification in nonsyndromic craniosynostosis
Abstract Nonsyndromic craniosynostosis (NSC) is the most common craniosynostosis with the primary defect being one or more fused sutures. In contrast to syndromic craniosynostosis, the etiopathogenesis of NSC is largely unknown. Here we show that autophagy, a major catabolic process required for the...
| Hlavní autoři: | , , , , , |
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| Médium: | Článek |
| Jazyk: | English |
| Vydáno: |
Nature Portfolio
2018-04-01
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| Edice: | Scientific Reports |
| On-line přístup: | https://doi.org/10.1038/s41598-018-24885-z |