Stereodivergent Synthesis of Aldol Products Using Pseudo-C<sub>2</sub> Symmetric <i>N</i>-benzyl-4-(trifluoromethyl)piperidine-2,6-dione

Stereodivergent Synthesis of Aldol Products Using Pseudo-C<sub>2</sub> Symmetric <i>N</i>-benzyl-4-(trifluoromethyl)piperidine-2,6-dione

The present article describes the successful performance of crossed aldol reactions of the CF<sub>3</sub>-containing pseudo-C<sub>2</sub> symmetric cyclic imide with various aldehydes. The utilization of HMPA as an additive attained the preferential formation of the <i>...

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Bibliographic Details
Main Authors: Rina Yada, Tomoko Kawasaki-Takasuka, Takashi Yamazaki
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Molecules
Subjects:
trifluoromethyl
pseudo-C<sub>2</sub> symmetry
aldol reactions
Michael addition reactions
Online Access:https://www.mdpi.com/1420-3049/29/21/5129

Internet

https://www.mdpi.com/1420-3049/29/21/5129

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