Histone Methyltransferases G9a/<i>Ehmt2</i> and GLP/<i>Ehmt1</i> Are Associated with Cell Viability and Poorer Prognosis in Neuroblastoma and Ewing Sarcoma

Histone Methyltransferases G9a/<i>Ehmt2</i> and GLP/<i>Ehmt1</i> Are Associated with Cell Viability and Poorer Prognosis in Neuroblastoma and Ewing Sarcoma

Changes in epigenetic programming have been proposed as being key events in the initiation and progression of childhood cancers. HMT euchromatic histone lysine methyltransferase 2 (G9a, EHMT2), which is encoded by the <i>G9a</i> (<i>Ehmt2</i>) gene, as well as its related pro...

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Bibliographic Details
Main Authors: Barbara Kunzler Souza, Natalia Hogetop Freire, Thiago Santos Monteiro, Alice Laschuk Herlinger, Mariane Jaeger, Matheus G. S. Dalmolin, Caroline Brunetto de Farias, Lauro Gregianin, André T. Brunetto, Algemir L. Brunetto, Carol J. Thiele, Rafael Roesler
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:International Journal of Molecular Sciences
Subjects:
G9a
GLP
histone methyltransferase
neuroblastoma
Ewing sarcoma
pediatric cancer
Online Access:https://www.mdpi.com/1422-0067/24/20/15242

Internet

https://www.mdpi.com/1422-0067/24/20/15242

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