A new approach for determining phase response curves reveals that Purkinje cells can act as perfect integrators.

Cerebellar Purkinje cells display complex intrinsic dynamics. They fire spontaneously, exhibit bistability, and via mutual network interactions are involved in the generation of high frequency oscillations and travelling waves of activity. To probe the dynamical properties of Purkinje cells we measu...

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Bibliographic Details
Main Authors: Elena Phoka, Hermann Cuntz, Arnd Roth, Michael Häusser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20442875/?tool=EBI