dRYBP contributes to the negative regulation of the Drosophila Imd pathway.

The Drosophila humoral innate immune response fights infection by producing antimicrobial peptides (AMPs) through the microbe-specific activation of the Toll or the Imd signaling pathway. Upon systemic infection, the production of AMPs is both positively and negatively regulated to reach a balanced...

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Bibliographic Details
Main Authors: Ricardo Aparicio, Claudine Neyen, Bruno Lemaitre, Ana Busturia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3626645?pdf=render