A strategy to incorporate prior knowledge into correlation network cutoff selection

A strategy to incorporate prior knowledge into correlation network cutoff selection

Correlation network inference is typically based on the significance of the correlation coefficients, but this procedure is not guaranteed to capture biological mechanisms. Here, the authors develop a cutoff selection algorithm that maximizes the overlap between inferred networks and prior knowledge...

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Bibliographic Details
Main Authors: Elisa Benedetti, Maja Pučić-Baković, Toma Keser, Nathalie Gerstner, Mustafa Büyüközkan, Tamara Štambuk, Maurice H. J. Selman, Igor Rudan, Ozren Polašek, Caroline Hayward, Hassen Al-Amin, Karsten Suhre, Gabi Kastenmüller, Gordan Lauc, Jan Krumsiek
Format: Article
Language:English
Published: Nature Portfolio 2020-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18675-3

Internet

https://doi.org/10.1038/s41467-020-18675-3

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