Parasitic helminth infections in humans modulate Trefoil Factor levels in a manner dependent on the species of parasite and age of the host.

Helminth infections, including hookworms and Schistosomes, can cause severe disability and death. Infection management and control would benefit from identification of biomarkers for early detection and prognosis. While animal models suggest that Trefoil Factor Family proteins (TFF2 and TFF3) and in...

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Bibliographic Details
Main Authors: Babatunde Adewale, Jonathan R Heintz, Christopher F Pastore, Heather L Rossi, Li-Yin Hung, Nurudeen Rahman, Jeff Bethony, David Diemert, James Ayorinde Babatunde, De'Broski R Herbert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-10-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009550