Structural insights into the HNF4 biology

Hepatocyte Nuclear Factor 4 (HNF4) is a transcription factor (TF) belonging to the nuclear receptor (NR) family that is expressed in liver, kidney, intestine and pancreas. It is a master regulator of liver-specific gene expression, in particular those genes involved in lipid transport and glucose me...

Description complète

Détails bibliographiques
Auteurs principaux: Brice Beinsteiner, Isabelle M. L. Billas, Dino Moras
Format: Article
Langue:English
Publié: Frontiers Media S.A. 2023-06-01
Collection:Frontiers in Endocrinology
Sujets:
Accès en ligne:https://www.frontiersin.org/articles/10.3389/fendo.2023.1197063/full