An Efficient UPLC-MS/MS Method Established to Detect Relugolix Concentration in Rat Plasma

Relugolix, a gonadotropin-releasing hormone (GnRH) receptor antagonist, has been well studied in the treatment of endometriosis symptomatic. It is mainly metabolized by the CYP3A subfamily of P450 enzymes, while minorly metabolized by CYP2C8. Daidzein in different dose groups exhibited a certain ind...

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Bibliographic Details
Main Authors: Liying Xing, Ya-nan Liu, Hongye Yao, Tingting Wang, Fuchen Xie, Shunbin Luo, Pingping Luo, Shengling Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.874973/full