Multi‐compartment metabolomics and metagenomics reveal major hepatic and intestinal disturbances in cancer cachectic mice

Multi‐compartment metabolomics and metagenomics reveal major hepatic and intestinal disturbances in cancer cachectic mice

Abstract Background Cancer cachexia is a multifactorial syndrome characterized by multiple metabolic dysfunctions. Besides the muscle, other organs such as the liver and the gut microbiota may also contribute to this syndrome. Indeed, the gut microbiota, an important regulator of the host metabolism...

Full description

Bibliographic Details
Main Authors: Sarah A. Pötgens, Morgane M. Thibaut, Nicolas Joudiou, Martina Sboarina, Audrey M. Neyrinck, Patrice D. Cani, Sandrine P. Claus, Nathalie M. Delzenne, Laure B. Bindels
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
Cancer cachexia
Liver steatosis
Gut microbiota
Gut transit
Short‐chain fatty acids
C26 model
Online Access:https://doi.org/10.1002/jcsm.12684

Internet

https://doi.org/10.1002/jcsm.12684

Similar Items