Identification of miRNA-Mediated Subpathways as Prostate Cancer Biomarkers Based on Topological Inference in a Machine Learning Process Using Integrated Gene and miRNA Expression Data

Identification of miRNA-Mediated Subpathways as Prostate Cancer Biomarkers Based on Topological Inference in a Machine Learning Process Using Integrated Gene and miRNA Expression Data

Accurately identifying classification biomarkers for distinguishing between normal and cancer samples is challenging. Additionally, the reproducibility of single-molecule biomarkers is limited by the existence of heterogeneous patient subgroups and differences in the sequencing techniques used to co...

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Bibliographic Details
Main Authors: Ziyu Ning, Shuang Yu, Yanqiao Zhao, Xiaoming Sun, Haibin Wu, Xiaoyang Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Genetics
Subjects:
machine learning
SVM
cancer
topological information
miRNA-mediated subpathway
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.656526/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.656526/full

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