Selective translational repression of HIV-1 RNA by Sam68DeltaC occurs by altering PABP1 binding to unspliced viral RNA

<p>Abstract</p> <p>HIV-1 structural proteins are translated from incompletely spliced 9 kb and 4 kb mRNAs, which are transported to the cytoplasm by Crm1. It has been assumed that once in the cytoplasm, translation of incompletely spliced HIV-1 mRNAs occurs in the same manner as ho...

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Bibliographic Details
Main Authors: Soros Vanessa, Marsh Kim, Cochrane Alan
Format: Article
Language:English
Published: BMC 2008-10-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/5/1/97