Zebrafish EEG predicts the efficacy of antiepileptic drugs

Zebrafish EEG predicts the efficacy of antiepileptic drugs

Background: Pharmacological evaluation of antiepileptic drugs (AEDs) using mammalian animals takes long time and is expensive. The zebrafish is a species commonly used to study brain functions, neurological diseases, and drug toxicity, and attracts more attention as an alternative animal model to su...

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Bibliographic Details
Main Authors: Jun-Nyeong Shin, Ki-Baek Lee, Woojae Butterworth, Soo-Kyung Park, Jung-Yeon Kim, Sohee Kim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
zebrafish
electroencephalogram (EEG)
drug screening
antiepileptic drug (AED)
efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1055424/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1055424/full

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