Procoagulant, tissue factor-bearing microparticles in bronchoalveolar lavage of interstitial lung disease patients: an observational study.

Procoagulant, tissue factor-bearing microparticles in bronchoalveolar lavage of interstitial lung disease patients: an observational study.

Coagulation factor Xa appears involved in the pathogenesis of pulmonary fibrosis. Through its interaction with protease activated receptor-1, this protease signals myofibroblast differentiation in lung fibroblasts. Although fibrogenic stimuli induce factor X synthesis by alveolar cells, the mechanis...

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Bibliographic Details
Main Authors: Federica Novelli, Tommaso Neri, Laura Tavanti, Chiara Armani, Concettina Noce, Fabio Falaschi, Maria Laura Bartoli, Federica Martino, Antonio Palla, Alessandro Celi, Pierluigi Paggiaro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4002423?pdf=render

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http://europepmc.org/articles/PMC4002423?pdf=render

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