Autophagy increase in Merosin-Deficient Congenital Muscular Dystrophy type 1A

Autophagy increase in Merosin-Deficient Congenital Muscular Dystrophy type 1A

The autophagy process recycles dysfunctional cellular components and protein aggregates by sequestering them in autophagosomes directed to lysosomes for enzymatic degradation. A basal level of autophagy is essential for skeletal muscle maintenance. Increased autophagy occurs in several forms of mus...

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Bibliographic Details
Main Authors: Mariangela Mastrapasqua, Roberta Rossi, Lucrezia De Cosmo, Annalisa Resta, Mariella Errede, Antonella Bizzoca, Stefania Zampatti, Nicoletta Resta, Emiliano Giardina, Maddalena Ruggieri, Daniela Virgintino, Tiziana Annese, Nicola Laforgia, Francesco Girolamo
Format: Article
Language:English
Published: PAGEPress Publications 2023-07-01
Series:European Journal of Translational Myology
Subjects:
autophagy
congenital muscular dystrophy
LC3
p62
Beclin-1
Online Access:https://pagepressjournals.org/index.php/bam/article/view/11501

Internet

https://pagepressjournals.org/index.php/bam/article/view/11501

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