Histones bundle F-actin filaments and affect actin structure.

Histones are small polycationic proteins complexed with DNA located in the cell nucleus. Upon apoptosis they are secreted from the cells and react with extracellular polyanionic compounds. Actin which is a polyanionic protein, is also secreted from necrotic cells and interacts with histones. We show...

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Bibliographic Details
Main Authors: Edna Blotnick, Asaf Sol, Andras Muhlrad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5573295?pdf=render