Magnetic Gold Nanoparticle-Labeled Heparanase Monoclonal Antibody and its Subsequent Application for Tumor Magnetic Resonance Imaging

Magnetic Gold Nanoparticle-Labeled Heparanase Monoclonal Antibody and its Subsequent Application for Tumor Magnetic Resonance Imaging

Abstract Heparanase (HPA) is ubiquitously expressed in various metastatic malignant tumors; previous studies have demonstrated that HPA was a potential tumor-associated antigen (TAA) for tumor immunotherapy. We sought to evaluate the feasibility of HPA as a common TAA for magnetic resonance imaging...

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Bibliographic Details
Main Authors: Ning Li, Meng-Meng Jie, Min Yang, Li Tang, Si-Yuan Chen, Xue-Mei Sun, Bo Tang, Shi-Ming Yang
Format: Article
Language:English
Published: SpringerOpen 2018-04-01
Series:Nanoscale Research Letters
Subjects:
Heparanase
Monoclonal antibody
Molecular imaging
Magnetic gold nanoparticle
Magnetic resonance imaging
Online Access:http://link.springer.com/article/10.1186/s11671-018-2518-1

Internet

http://link.springer.com/article/10.1186/s11671-018-2518-1

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