Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy

Evaluation of the immunomodulatory effects of interleukin-10 on peripheral blood immune cells of COVID-19 patients: Implication for COVID-19 therapy

ObjectiveSeveral therapies with immune-modulatory functions have been proposed to reduce the overwhelmed inflammation associated with COVID-19. Here we investigated the impact of IL-10 in COVID-19, through the ex-vivo assessment of the effects of exogenous IL-10 on SARS-CoV-2-specific-response using...

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Bibliographic Details
Main Authors: Saeid Najafi-Fard, Elisa Petruccioli, Chiara Farroni, Linda Petrone, Valentina Vanini, Gilda Cuzzi, Andrea Salmi, Anna Maria Gerarda Altera, Assunta Navarra, Tonino Alonzi, Emanuele Nicastri, Fabrizio Palmieri, Gina Gualano, Valentina Carlini, Douglas McClain Noonan, Adriana Albini, Delia Goletti
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
spike
IL-10
whole-blood
Natutal Killer Cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.984098/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.984098/full

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