Distinct patterns of whole blood transcriptional responses are induced in mice following immunisation with adenoviral and poxviral vector vaccines encoding the same antigen

Abstract Background Viral vectors, including adenovirus (Ad) and modified vaccinia Ankara (MVA), have gained increasing attention as vaccine platforms in recent years due to their capacity to express antigens from a wide array of pathogens, their rapid induction of humoral and cellular protective im...

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Bibliographic Details
Main Authors: Dylan Sheerin, Christina Dold, Daniel O’Connor, Andrew J. Pollard, Christine S. Rollier
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Genomics
Online Access:https://doi.org/10.1186/s12864-021-08061-8