Spillage of bacterial products during colon surgery increases the risk of liver metastases development in a rat colon carcinoma model.

Spillage of bacterial products during colon surgery increases the risk of liver metastases development in a rat colon carcinoma model.

Surgical resection of the primary tumor provides the best chance of cure for patients with colorectal carcinoma (CRC). However, bacterial translocation during intestinal surgery has been correlated with poor long-term oncological outcome. Therefore, we investigated the influence of bacterial contami...

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Bibliographic Details
Main Authors: Simran Grewal, Rianne Korthouwer, Marijn Bögels, Rens Braster, Niels Heemskerk, Andries E. Budding, Stephan M. Pouw, Jack van Horssen, Marjolein Ankersmit, Jeroen Meijerink, Petrousjka van den Tol, Steven Oosterling, Jaap Bonjer, Nuray Gül, Marjolein van Egmond
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:OncoImmunology
Subjects:
colorectal tumor surgery
bacterial translocation
macrophages
liver metastases
reactive oxygen species
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1461302

Internet

http://dx.doi.org/10.1080/2162402X.2018.1461302

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