Chlamydial entry involves TARP binding of guanine nucleotide exchange factors.

Chlamydia trachomatis attachment to cells induces the secretion of the elementary body-associated protein TARP (Translocated Actin Recruiting Protein). TARP crosses the plasma membrane where it is immediately phosphorylated at tyrosine residues by unknown host kinases. The Rac GTPase is also activat...

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Bibliographic Details
Main Authors: B Josh Lane, Charla Mutchler, Souhaila Al Khodor, Scott S Grieshaber, Rey A Carabeo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2279300?pdf=render