Chlamydial entry involves TARP binding of guanine nucleotide exchange factors.
Chlamydia trachomatis attachment to cells induces the secretion of the elementary body-associated protein TARP (Translocated Actin Recruiting Protein). TARP crosses the plasma membrane where it is immediately phosphorylated at tyrosine residues by unknown host kinases. The Rac GTPase is also activat...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-03-01
|
Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC2279300?pdf=render |