Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway

Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway

The slmap gene is alternatively spliced to generate many isoforms that are abundant in developing myocardium. The largest protein isoform SLMAP3 is ubiquitously expressed and has been linked to cardiomyopathy, Brugada syndrome and Hippo signaling. To examine any role in cardiogenesis, mice homozygou...

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Bibliographic Details
Main Authors: Taha Rehmani, Ana Paula Dias, Marsel Kamal, Maysoon Salih, Balwant S. Tuana
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
SLMAP3
STRIPAK complex
Hippo signaling
cardiac morphogenesis
Online Access:https://www.mdpi.com/1422-0067/25/5/2888

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https://www.mdpi.com/1422-0067/25/5/2888

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