Motoneuron firing in amyotrophic lateral sclerosis (ALS)

Amyotrophic lateral sclerosis is an inexorably progressive neurodegenerative disorder involving the classical motor system and the frontal effector brain, causing muscular weakness and atrophy, with variable upper motor neuron signs and often an associated fronto-temporal dementia. The physiological...

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Bibliographic Details
Main Authors: Mamede eDe Carvalho, Andrew eEisen, Charles eKrieger, Michael eSwash
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Human Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00719/full