Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma

Neoadjuvant chemoradiation alters the immune microenvironment in pancreatic ductal adenocarcinoma

Patients with pancreatic ductal adenocarcinoma (PDAC) have a grim prognosis despite complete surgical resection and intense systemic therapies. While immunotherapies have been beneficial with many different types of solid tumors, they have almost uniformly failed in the treatment of PDAC. Understand...

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Bibliographic Details
Main Authors: Robyn D. Gartrell, Thomas Enzler, Pan S. Kim, Benjamin T. Fullerton, Ladan Fazlollahi, Andrew X. Chen, Hanna E. Minns, Subha Perni, Stuart P. Weisberg, Emanuelle M. Rizk, Samuel Wang, Eun Jeong Oh, Xinzheng V. Guo, Codruta Chiuzan, Gulam A. Manji, Susan E. Bates, John Chabot, Beth Schrope, Michael Kluger, Jean Emond, Raul Rabadán, Donna Farber, Helen E. Remotti, David P. Horowitz, Yvonne M. Saenger
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:OncoImmunology
Subjects:
Tumor microenvironment
tumor-infiltrating lymphocytes
T regulatory cells
biomarkers
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2066767

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2022.2066767

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