Sequencing intractable DNA to close microbial genomes.

Advancement in high throughput DNA sequencing technologies has supported a rapid proliferation of microbial genome sequencing projects, providing the genetic blueprint for in-depth studies. Oftentimes, difficult to sequence regions in microbial genomes are ruled "intractable" resulting in...

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Bibliographic Details
Main Authors: Richard A Hurt, Steven D Brown, Mircea Podar, Anthony V Palumbo, Dwayne A Elias
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3409199?pdf=render