An agent-based model of cellular dynamics and circadian variability in human endotoxemia.

As cellular variability and circadian rhythmicity play critical roles in immune and inflammatory responses, we present in this study an agent-based model of human endotoxemia to examine the interplay between circadian controls, cellular variability and stochastic dynamics of inflammatory cytokines....

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Bibliographic Details
Main Authors: Tung T Nguyen, Steve E Calvano, Stephen F Lowry, Ioannis P Androulakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3559552?pdf=render