PAI-1 regulates AT2-mediated re-alveolarization and ion permeability

PAI-1 regulates AT2-mediated re-alveolarization and ion permeability

Abstract Background Acute lung injury is characterized by overwhelmingly elevated PAI-1 in both lung edema fluid and the circulating system. The role of increased PAI-1, encoded by Serpine1 gene, in the regeneration of injured lung epithelium has not been understood completely. This study aimed to i...

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Bibliographic Details
Main Authors: Gibran Ali, Mo Zhang, Jianjun Chang, Runzhen Zhao, Yang Jin, Jiwang Zhang, Hong-Long Ji
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Stem Cell Research & Therapy
Subjects:
Serpine1
Proliferation
Differentiation
Organoids
Re-alveolarization
Online Access:https://doi.org/10.1186/s13287-023-03414-4

Internet

https://doi.org/10.1186/s13287-023-03414-4

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