RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue

RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue

Abstract Background Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects the motor neuromuscular system leading to complete paralysis and premature death. The multifactorial nature of ALS that involves both cell-autonomous and non-cell-autonomous processes cont...

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Bibliographic Details
Main Authors: Antonio Vallarola, Francesca Sironi, Massimo Tortarolo, Noemi Gatto, Roberta De Gioia, Laura Pasetto, Massimiliano De Paola, Alessandro Mariani, Supurna Ghosh, Richard Watson, Andreas Kalmes, Valentina Bonetto, Caterina Bendotti
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Journal of Neuroinflammation
Subjects:
ALS
RNS60
Neuroinflammation
Oxidative stress
Online Access:http://link.springer.com/article/10.1186/s12974-018-1101-0

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http://link.springer.com/article/10.1186/s12974-018-1101-0

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