Development of a genetic risk score to predict the risk of hypertension in European adolescents from the HELENA study

IntroductionFrom genome wide association study (GWAS) a large number of single nucleotide polymorphisms (SNPs) have previously been associated with blood pressure (BP) levels. A combination of SNPs, forming a genetic risk score (GRS) could be considered as a useful genetic tool to identify individua...

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Main Authors: Gloria Pérez-Gimeno, Miguel Seral-Cortes, Sergio Sabroso-Lasa, Luis Mariano Esteban, Empar Lurbe, Laurent Béghin, Frederic Gottrand, Aline Meirhaeghe, Manon Muntaner, Anthony Kafatos, Dénes Molnár, Catherine Leclercq, Kurt Widhalm, Mathilde Kersting, Esther Nova, Diego F. Salazar-Tortosa, Marcela Gonzalez-Gross, Christina Breidenassel, Kathrin Sinningen, Thaïs De Ruyter, Idoia Labayen, Azahara I. Rupérez, Gloria Bueno-Lozano, Luis A. Moreno
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1118919/full