A New Synthetic Compound, 2-OH, Enhances Interleukin-2 and Interferon-γ Gene Expression in Human Peripheral Blood Mononuclear Cells

A New Synthetic Compound, 2-OH, Enhances Interleukin-2 and Interferon-γ Gene Expression in Human Peripheral Blood Mononuclear Cells

A new synthetic compound, 6-hydroxy-2-tosylisoquinolin-1(2H)-one (2-OH), was selected for immunopharmacological activity tests. The effects of 2-OH on human peripheral blood mononuclear cell (PBMC) proliferation were determined by tritiated thymidine uptake. Compared to phytohemagglutinin (PHA; 5 μg...

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Bibliographic Details
Main Authors: Woan-Fang Tzeng, Rwei-Fen S. Huang, Su-Jane Wang, Jyh-Yih Leu, Yih-Fong Liew, Shang-Shing P. Chou, Shiu-Huey Chou, Yuh-Chi Kuo
Format: Article
Language:English
Published: MDPI AG 2009-07-01
Series:Molecules
Subjects:
PBMC
proliferation
IL-2
Online Access:http://www.mdpi.com/1420-3049/14/7/2345/

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http://www.mdpi.com/1420-3049/14/7/2345/

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