Nestin Expression Affects Resistance to Chemotherapy and Clinical Outcome in Small Cell Lung Cancer

Nestin Expression Affects Resistance to Chemotherapy and Clinical Outcome in Small Cell Lung Cancer

Objectives: Small cell lung cancer (SCLC) is an aggressive and highly metastatic lung cancer subtype. Nestin is a member of the intermediate filament family and serves as a potential proliferative and multipotency marker in neural progenitor and stem cells. Aberrant expression of nestin is linked to...

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Bibliographic Details
Main Authors: Kazuki Sone, Ken Maeno, Ayako Masaki, Eiji Kunii, Osamu Takakuwa, Yusuke Kagawa, Akira Takeuchi, Satoshi Fukuda, Takehiro Uemura, Kensuke Fukumitsu, Yoshihiro Kanemitsu, Hirotsugu Ohkubo, Masaya Takemura, Yutaka Ito, Tetsuya Oguri, Hiroshi Inagaki, Akio Niimi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Oncology
Subjects:
nestin
small cell lung cancer
chemotherapy
resistance
immunohistochemistry
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01367/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.01367/full

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