Irisin Attenuates Muscle Impairment during Bed Rest through Muscle-Adipose Tissue Crosstalk

Irisin Attenuates Muscle Impairment during Bed Rest through Muscle-Adipose Tissue Crosstalk

The detrimental effect of physical inactivity on muscle characteristics are well known. Irisin, an exercise-induced myokine cleaved from membrane protein fibronectin type III domain-containing protein-5 (FNDC5), mediates at least partially the metabolic benefits of exercise. This study aimed to asse...

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Bibliographic Details
Main Authors: Andrea D’Amuri, Juana Maria Sanz, Stefano Lazzer, Rado Pišot, Bostjan Šimunič, Gianni Biolo, Giovanni Zuliani, Mladen Gasparini, Marco Narici, Bruno Grassi, Carlo Reggiani, Edoardo Dalla Nora, Angelina Passaro
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Biology
Subjects:
inactivity
FNDC5 gene expression
myokines
sarcopenia
muscle fiber
Online Access:https://www.mdpi.com/2079-7737/11/7/999

Internet

https://www.mdpi.com/2079-7737/11/7/999

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