The Role of the Transforming Growth Factor-β Signaling Pathway in Gastrointestinal Cancers

The Role of the Transforming Growth Factor-β Signaling Pathway in Gastrointestinal Cancers

Transforming growth factor-β (TGF-β) has attracted attention as a tumor suppressor because of its potent growth-suppressive effect on epithelial cells. Dysregulation of the TGF-β signaling pathway is considered to be one of the key factors in carcinogenesis, and genetic alterations affecting TGF-β s...

Full description

Bibliographic Details
Main Authors: Tasuku Matsuoka, Masakazu Yashiro
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Biomolecules
Subjects:
transforming growth factor-β
smad
gastrointestinal cancers
epithelial-mesenchymal transition
tumor microenvironment
immune evasion
Online Access:https://www.mdpi.com/2218-273X/13/10/1551

Internet

https://www.mdpi.com/2218-273X/13/10/1551

Similar Items