Modeling of ionizing radiation-induced chromosome aberration and tumor prevalence based on two classes of DNA double-strand breaks clustering in chromatin domains

Modeling of ionizing radiation-induced chromosome aberration and tumor prevalence based on two classes of DNA double-strand breaks clustering in chromatin domains

There has been some controversy over the use of radiobiological models when modeling the dose-response curves of ionizing radiation (IR)-induced chromosome aberration and tumor prevalence, as those curves usually show obvious non-targeted effects (NTEs) at low doses of high linear energy transfer (L...

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Bibliographic Details
Main Authors: Lei Zhao, Aiping Tang, Fei Long, Dong Mi, Yeqing Sun
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Ionizing radiation
Chromosome aberration
Tumor prevalence
Non-targeted effect
Radiobiological model
Relative biological effectiveness
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323005420

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http://www.sciencedirect.com/science/article/pii/S0147651323005420

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