Connexins and pannexins: New insights into microglial functions and dysfunctions

In a physiological context, microglia adopt a resting phenotype that is associated with the production of anti-inflammatory and neurotrophic factors. In response to a wide variety of insults, they shift to the activated phenotype that is necessary for the proper restoration of brain homeostasis. Whe...

Full description

Bibliographic Details
Main Authors: Rosario Gajardo-Gómez, Valeria C Labra, Juan Andrés Orellana
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00086/full