Pancreatic Cancer with Mutation in BRCA1/2, MLH1, and APC Genes: Phenotype Correlation and Detection of a Novel Germline BRCA2 Mutation

Pancreatic Cancer with Mutation in BRCA1/2, MLH1, and APC Genes: Phenotype Correlation and Detection of a Novel Germline BRCA2 Mutation

Pancreatic ductal adenocarcinoma (PDAC) is the seventh leading cause of cancer death worldwide; most of cases are sporadic, however about 5% to 10% report a hereditary predisposition. Several hereditary syndromes have been associated with familial pancreatic cancer (FPC) onset, including hereditary...

Full description

Bibliographic Details
Main Authors: Maria Teresa Vietri, Giovanna D’Elia, Gemma Caliendo, Luisa Albanese, Giuseppe Signoriello, Claudio Napoli, Anna Maria Molinari
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Genes
Subjects:
pancreatic ductal adenocarcinoma
hereditary breast and ovarian cancer syndrome
hereditary nonpolyposis colon cancer syndrome
familial adenomatous polyposis
BRCA genes
MMR genes
Online Access:https://www.mdpi.com/2073-4425/13/2/321

Internet

https://www.mdpi.com/2073-4425/13/2/321

Similar Items