Modeling tumors of the peripheral nervous system associated with Neurofibromatosis type 1: Reprogramming plexiform neurofibroma cells

Modeling tumors of the peripheral nervous system associated with Neurofibromatosis type 1: Reprogramming plexiform neurofibroma cells

Plexiform neurofibromas (pNFs) are benign tumors of the peripheral nervous system (PNS) that can progress towards a deadly soft tissue sarcoma termed malignant peripheral nerve sheath tumor (MPNST). pNFs appear during development in the context of the genetic disease Neurofibromatosis type 1 (NF1) d...

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Bibliographic Details
Main Authors: Helena Mazuelas, Meritxell Carrió, Eduard Serra
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Stem Cell Research
Subjects:
Cancer predisposition syndrome
Neurofibromatosis
Plexiform neurofibroma
iPSC
Neural crest
Schwann cell
Online Access:http://www.sciencedirect.com/science/article/pii/S187350612030369X

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http://www.sciencedirect.com/science/article/pii/S187350612030369X

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