Evaluation of CRISPR gene-editing tools in zebrafish

Abstract Background Zebrafish have practical features that make them a useful model for higher-throughput tests of gene function using CRISPR/Cas9 editing to create ‘knockout’ models. In particular, the use of G0 mosaic mutants has potential to increase throughput of functional studies significantly...

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Bibliographic Details
Main Authors: José M. Uribe-Salazar, Gulhan Kaya, Aadithya Sekar, KaeChandra Weyenberg, Cole Ingamells, Megan Y. Dennis
Format: Article
Language:English
Published: BMC 2022-01-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-021-08238-1