Brain-derived neurotrophic factor promotes immune reconstitution following radiation injury via activation of bone marrow mesenchymal stem cells.

Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family which has been extensively studied for its roles in neural development, long-term memory, brain injury, and neurodegenerative diseases. BDNF signaling through tropomyosin receptor kinase B (TrkB) stimulates neuron...

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Bibliographic Details
Main Authors: Guru Prasad Sharma, Anne C Frei, Jayashree Narayanan, Tracy Gasperetti, Dana Veley, Asma Amjad, Katherine Albano, Brian L Fish, Heather A Himburg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0259042