The creation and selection of mutations resistant to a gene drive over multiple generations in the malaria mosquito.

Gene drives have enormous potential for the control of insect populations of medical and agricultural relevance. By preferentially biasing their own inheritance, gene drives can rapidly introduce genetic traits even if these confer a negative fitness effect on the population. We have recently develo...

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Bibliographic Details
Main Authors: Andrew M Hammond, Kyros Kyrou, Marco Bruttini, Ace North, Roberto Galizi, Xenia Karlsson, Nace Kranjc, Francesco M Carpi, Romina D'Aurizio, Andrea Crisanti, Tony Nolan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC5648257?pdf=render