Carnosine Protects against Cerebral Ischemic Injury by Inhibiting Matrix-Metalloproteinases

Carnosine Protects against Cerebral Ischemic Injury by Inhibiting Matrix-Metalloproteinases

Stroke is one of the leading causes of death and disability worldwide. However, treatment options for ischemic stroke remain limited. Matrix-metalloproteinases (MMPs) contribute to brain damage during ischemic strokes by disrupting the blood-brain barrier (BBB) and causing brain edemas. Carnosine, a...

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Bibliographic Details
Main Authors: Eun-Hye Kim, Eun-Sun Kim, Donggeun Shin, Donghyun Kim, Sungbin Choi, Young-Jun Shin, Kyeong-A Kim, Dabi Noh, Ahmet B. Caglayan, G.K. Rajanikant, Arshad Majid, Ok-Nam Bae
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
ischemic stroke
matrix-metalloproteinases
carnosine
brain edema
tight junction
Online Access:https://www.mdpi.com/1422-0067/22/14/7495

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https://www.mdpi.com/1422-0067/22/14/7495

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