Computational investigations on target-site searching and recognition mechanisms by thymine DNA glycosylase during DNA repair process
DNA glycosylase, as one member of DNA repair machineries, plays an essential role in correcting mismatched/damaged DNA nucleotides by cleaving the N-glycosidic bond between the sugar and target nucleobase through the base excision repair (BER) pathways. Efficient corrections of these DNA lesions are...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
China Science Publishing & Media Ltd.
2022-05-01
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Series: | Acta Biochimica et Biophysica Sinica |
Subjects: | |
Online Access: | https://www.sciengine.com/doi/10.3724/abbs.2022050 |