Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis

Abstract Background Osteoarthritis (OA) is a common chronic disease characterized by chronic inflammation and extracellular matrix degradation. Indole-3-propionic acid (IPA) is a tryptophan metabolite secreted by intestinal flora, which can exert anti-inflammatory effects in a variety of diseases. I...

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Bibliographic Details
Main Authors: Huangming Zhuang, Xunshan Ren, Fuze Jiang, Panghu Zhou
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-023-00614-9