Safety and immunogenicity of a recombinant Staphylococcus aureus α-toxoid and a recombinant Panton-Valentine leukocidin subunit, in healthy adults

Safety and immunogenicity of a recombinant Staphylococcus aureus α-toxoid and a recombinant Panton-Valentine leukocidin subunit, in healthy adults

We conducted a randomized, double-blind, placebo-controlled dose-escalation study in healthy adults to evaluate the safety and immunogenicity of recombinant Staphylococcus aureus candidate vaccine antigens, recombinant α-toxoid (rAT) and a sub-unit of Panton-Valentine leukocidin (rLukS-PV). 176 subj...

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Bibliographic Details
Main Authors: Michael L. Landrum, Tahaniyat Lalani, Minoo Niknian, Jason D. Maguire, Duane R. Hospenthal, Ali Fattom, Kimberly Taylor, Jamie Fraser, Kenneth Wilkins, Michael W. Ellis, Paul D. Kessler, Rafaat E. F. Fahim, David R. Tribble
Format: Article
Language:English
Published: Taylor & Francis Group 2017-04-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
bacterial vaccine
recombinant α-toxoid
recombinant panton-valentine leukocidin
staphylococcus aureus
Online Access:http://dx.doi.org/10.1080/21645515.2016.1248326

Internet

http://dx.doi.org/10.1080/21645515.2016.1248326

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