Neuronal-Derived EV Biomarkers Track Cognitive Decline in Alzheimer’s Disease

Neuronal-Derived EV Biomarkers Track Cognitive Decline in Alzheimer’s Disease

The hallmarks of Alzheimer’s disease (AD) pathology are senile plaques containing amyloid-beta (Aβ) and neurofibrillary tangles containing hyperphosphorylated tau. Additional pathologies often co-exist, whereas multiple pathogenic mechanisms are involved in AD, especially synaptic degeneration, whic...

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Bibliographic Details
Main Authors: Erden Eren, Jeannie-Marie Leoutsakos, Juan Troncoso, Constantine G. Lyketsos, Esther S. Oh, Dimitrios Kapogiannis
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
extracellular vesicles
autopsy
Alzheimer’s disease
mixed pathology
exosomes
neuron-derived extracellular vesicles
Online Access:https://www.mdpi.com/2073-4409/11/3/436

Internet

https://www.mdpi.com/2073-4409/11/3/436

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