Population pharmacokinetics of primaquine and its metabolites in African males
Abstract Background Primaquine (PQ) is the prototype 8-aminoquinoline drug, a class which targets gametocytes and hypnozoites. The World Health Organization (WHO) recommends adding a single low dose of primaquine to the standard artemisinin-based combination therapy (ACT) in order to block malaria t...
Main Authors: | , , , , , , , , , , , , |
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格式: | Article |
語言: | English |
出版: |
BMC
2024-05-01
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叢編: | Malaria Journal |
主題: | |
在線閱讀: | https://doi.org/10.1186/s12936-024-04979-y |