Preclinical therapeutics ex ovo quail eggs as a biomimetic automation-ready xenograft platform
Abstract Preclinical cancer research ranges from in vitro studies that are inexpensive and not necessarily reflective of the tumor microenvironment to mouse studies that are better models but prohibitively expensive at scale. Chorioallantoic membrane (CAM) assays utilizing Japanese quail (Coturnix j...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-12-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-02509-3 |