Cyanidin-3-glucoside inhibits ferroptosis in renal tubular cells after ischemia/reperfusion injury via the AMPK pathway

Cyanidin-3-glucoside inhibits ferroptosis in renal tubular cells after ischemia/reperfusion injury via the AMPK pathway

Abstract Background Ferroptosis, which is characterized by lipid peroxidation and iron accumulation, is closely associated with the pathogenesis of acute renal injury (AKI). Cyanidin-3-glucoside (C3G), a typical flavonoid that has anti-inflammatory and antioxidant effects on ischemia‒reperfusion (I/...

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Bibliographic Details
Main Authors: Yi-Wei Du, Xiao-Kang Li, Ting-Ting Wang, Lu Zhou, Hui-Rong Li, Lan Feng, Heng Ma, Hong-Bao Liu
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Molecular Medicine
Subjects:
Acute kidney injury (AKI)
AMP-activated protein kinase (AMPK)
Cyanidin-3-glucoside (C3G)
Ferroptosis
Ischemia
Lipid peroxidation
Online Access:https://doi.org/10.1186/s10020-023-00642-5

Internet

https://doi.org/10.1186/s10020-023-00642-5

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